Lactulose is a type of laxative used to manage a disorder in cats and dogs called hepatic encephalopathy. It is a sugar solution created from two sugars and unlike other sugars, it is not absorbed into the blood, but passes unchanged into the large intestine. When it reaches the large intestine, it is broken down by a variety of acids. The acids draw water into the colon and they act as softening agents, increasing the volume and softening the stool. The result is a laxative effect. Lactulose can help reduce ammonia that builds up in the blood.

Although constipation is not life-threatening, it is uncomfortable and can leave an animal feeling bloated or sluggish.

Lactulose has also been proven effective in treating cases of feline megacolon. This is a disorder of the bowels that leads to chronic constipation. The disorder is generally progressive. Stool remains in the colon and becomes drier and harder, causing it to be more difficult to pass. Under these circumstances, defecation can become virtually impossible. Cats with megacolon show signs of abdominal discomfort, frequent visits to the litter box, inappetance, straining, and vomiting. Lactulose softens the stool and helps restore normal bowel movement.
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